A number of clinical trials suggest that Pycnogenol may lower blood glucose if taken daily for at least 12 weeks. Studies have found that when taken along with an inhaler, Pycnogenol can reduce leukotrienes, helping to relieve lung inflammation and limit frequency of inhaler use., Many people develop osteoarthritis as they age. She is a strong advocate of integrating scientific knowledge and holistic medicine. 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Clearer skin, healthier hair there are a lot of claims about the health benefits of biotin. But what makes this miracle ingredient so amazing? Pycnogenol treatment resulted in more normal-looking sperm. New research has shown promising results for those dealing with erectile dysfunction (ED) and diabetes. Clinical research suggests that Pycnogenol is possibly effective for improving athletic performance. The study concluded that Pycnogenol can prevent cramps, muscular pain at rest, and pain after/during exercise healthy people or those with diabetes or claudication. In a double-blind, placebo-controlled, randomized, crossover study, 50 patients with erectile dysfunction (ED) were treated with either L-arginine plus Pycnogenol or placebo for a month. A combination supplement (pycnogenol with collagen, coenzyme Q10, and other ingredients) reduced skin aging, elasticity, hydration, and tonicity in a study of 30 women [65]. It also slightly decreased blood pressure and increased testosterone [67]. Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. Pine bark extract is composed of 80% to 85% proanthocyanidins, the monomers catechin and taxifolin (5%), and phenolic acids, including derivatives of benzoic and cinnamic acids (2% to 4%). Trees of this pine have been naturalized in Australia and New Zealand, where most Enzogenol is now made [7]. 3. Gotu Kola: Health Benefits, Side Effects, Uses, and More - WebMD 10 Day Erection Delay Sex Pills. Pycnogenol acts as a sustained-release formulation. Sort By. Grapes: Health Benefits, Nutrition, Recipes and Risks - Dr. Axe With time, the participants were able to handle more UV radiation without experiencing skin damage [63]. This includes supporting healthy blood circulation, acting as a natural anti-inflammatory, helping to generate collagen and hyaluronic acid for improved skin health and aiding in the production of endothelial nitric oxide which helps to dilate blood . , Allergy: "Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. In the placebo group, the retinopathy worsened; whereas, in the Pycnogenol-treated group, there was no deterioration. In 19 smokers, increased platelet aggregation was more significantly reduced by 200 mg than either 10 mg or 100 mg of Pycnogenol. Another study of 47 women found that supplementing with 30 mg Pycnogenol twice daily for over 1 month may reduce menstrual pain [73]. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. New Study: Daily Use of Pycnogenol Provides Benefits for Men Managing . The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). They also had normalized fasting glucose levels and blood pressure, which can also reduce a persons risk of heart problems. are clickable links to medically peer-reviewed studies. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. High levels of both of these are considered risk factors for heart disease. Cigarette smoking increases platelet aggregation. Natural Factors Pycnogenol 100mg 30 Veggie Caps. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. Researchers suggest that Pycnogenol may reduce cough, night-awakenings, improve airway flow, and the need for additional asthma medication [16]. They could interact with medicines to suppress the immune system, chemotherapy drugs, and blood thinners. However, it can also be used topically. Pycnogenol: Uses and Risks - WebMD 32 Pycnogenol & Pine Bark Extract Benefits + Dosage Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. but is for informational and educational purposes alone. Skin irritation. (11, 12), While both eliminate pain, the pine bark extract is a far better choice. Pycnogenol also treatment improved blood vessel function. Pycnogenol (100 mg/day) supplementation may decrease symptoms of the common cold and speed up recovery, according to a clinical trial of 146 people. According to researchers, it may help prevent the rise in free radicals typically seen after exercise, which could cause muscle fatigue and damage [9]. After taking a break for one to two weeks, they can start taking it again for several weeks. This study adds to a body of research showing the benefits of Pycnogenol . Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. It can also stabilize mast cells, which release histamine and trigger allergic reactions. One way to add some extra flavor and nutrients to your day is by adding prune juice to your diet. There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. Chemistry. Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. Interactions. Pine bark extract is usually taken by mouth in capsule form. Are there any risks to taking it? Based on another study of 6 trained and 7 untrained people, an antioxidant combination product containing Pycnogenol (Lactaway) may increase endurance. Pycnogenol may reduce glucose levels, but it doesnt appear to increase insulin production or insulin sensitivity. Consequently, blood pressure is lowered. Folic Acid Benefits, Deficiency, Foods, Side Effects, More - Dr. Axe The researchers of the study propose that pycnogenol may reduce pain and cramps during retraining and rehabilitation in people with blood vessel problems [11]. (2004). Traditionally, people might drink a brew made from pine bark -- rich in pycnogenol -- as a treatment. This article explains which supplements are believed to be safe during pregnancy and which ones you should avoid. Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. Ana has many years of experience in clinical research and health advising. (5). Forty patients were treated with either 600 mg chestnut seed extract a day or 360 mg Pycnogenol a day over a period of four weeks. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. Flavonoids and proanthocyanidins within these fruits can . If you choose to use Pycnogenol, follow the dosage instructions on the label. Higher doses (200 mg/day) may improve blood vessel health and function after 8 weeks according to a study of 23 people with heart disease [38]. The study participants symptoms started to return a month after they stopped taking pine bark extract. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. For people who have symptoms that are more severe, traditional medicine is probably more effective. In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. A clinically studied blend of Pycnogenol and a special bilberry extract (called Mirtogenol ) has been shown to provide benefits for vision and eye health. However, in all the above studies insulin levels did not change. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. Pycnogenol: A miracle component in reducing ageing and skin disorders. Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. What Are These Tiny Red Spots on My Skin (Petechiae)? In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [42, 43]. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Note that the numbers in parentheses (1, 2, etc.) The combination of Panax ginseng and vitamin E also appears to have an effect. It may cause side effects such as: Dizziness. Animal studies have found that gotu kola makes it harder . Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. This article reviews tongkat ali, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. SelfDecode is a personalized health report service, $31.99. (7). Pycnogenol may help reduce symptoms of melasma, a form of hyperpigmentation, possibly because it protects against UV rays. For most people, pine bark extract doesnt cause any side effects. Add to Cart. However, it's always a good idea to start with a low dose so you can monitor how your body responds. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [41]. There is currently insufficient evidence to determine what a safe and effective dose of lysine is for specific conditions. Pycnogenol Benefits, Dosage & Side Effects - Ayur Times This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. Millions are hospitalized each year for . 10 Day Erection Delay Sex Pills - Sharda University Another group of men who took just l-arginine didnt improve [66]. In addition to general healthy eating, some specific vitamins and minerals may help improve ADHD. In a good-quality study, 77 patients with osteoarthritis were treated with 100 mg of Pycnogenol daily and 79 patients were treated with placebo for three months. Although these may still be high quality, the active compounds are more likely to vary. Researchers suggest it may boost sustained attention, memory, executive functions, mood, and reduce oxidative stress [19]. Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. It can also be used for local application on the skin without the risk of side effects. According to some researchers, when you take Pycnogenol [8]: Research suggests that Pycnogenol may protect cells in the body against oxidative stress. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. Blazs G, et al. Pycnogenol French maritime pine bark extract's 4 basic properties.